oval cell

Relative Analysis between the Hepatic Oval Cell and Primary Hepatic Carcinoma

肝卵圆细胞与原发性肝癌相关性分析

Results Hepatic oval cell proliferation models from three rat strains were successfully established .

结果成功建立三种品系大鼠肝脏卵圆细胞增殖模型。

Hepatocyte Growth Factor , Oval Cell , Bone Marrow Cell and Liver Regeneration

肝细胞生长因子、卵圆细胞、骨髓细胞和肝再生

The regulatory mechanism of liver oval cell differentiation

肝卵圆细胞分化调控机制的研究进展

Investigation of the role of hepatic oval cell in primary hepatocarcinogenesis using specific Y chromosome

利用特异性Y染色体研究肝脏卵圆细胞在原发性肝癌发生中的作用

Effects of 2-acetaminofluorene on hepatic oval cell proliferation in rats

2-乙酰氨基芴对大鼠肝卵圆细胞增殖模型的影响

The Stimulation of Astragalus Membranaceus on Rats ' Hepatic Oval Cell Growth Cultured in vitro

黄芪刺激体外培养的大鼠肝卵圆细胞生长的作用

Observation of big and small mitosis and oval cell emergence in regenerated liver tissue after partial hepatectomy

小鼠单纯肝切除后再生肝组织内大小核分裂相和卵圆细胞的观察

Effect of PNS on the Expression of CX / GJIC in Rat Liver for Hepatic Oval Cell Proliferation

三七总皂甙对大鼠肝卵圆细胞增殖肝脏CX/GJIC的影响

Objective To select the rat strain relatively more suitable for model establishment by comparison of hepatic oval cell proliferation models from different rat strains .

目的对不同品系大鼠肝卵圆细胞增殖模型进行比较，筛选建模效率较高的大鼠品系。

The Experimental Study of Hepatic Oval Cell Lines Transformed into Liver Cancer Following Transfection with HBx Gene and Treatment with Aflatoxin B1 in Vivo

HBx联合AFB1诱导肝卵圆细胞体内转化为肝癌的实验研究

Methods Male Wistar rats weighing 150 ~ 200 g were used to establish a model for hepatic oval cell proliferation ( 2-AAF / PH ) .

方法选择体重150~200g的雄性Wistar大鼠，建立肝卵圆细胞增殖模型（2-AAF/PH）。

To investigate the role of hepatocyte growth factor in liver regeneration and to study the interaction between hepatocyte growth factor and oval cell , bone marrow cell , respectively .

进一步研究肝细胞生长因子在肝脏再生中的作用以及肝细胞生长因子分别和卵圆细胞、骨髓细胞的相互作用。

Conclusion Among the three rat strains most commonly used for hepatic oval cell proliferation models , hepatic oval cells from F344 rats have the highest activation efficiency .

结论在用于建立肝脏卵圆细胞增殖模型最为常见的三种品系大鼠中，F344大鼠所建模型的肝脏卵圆细胞活化效率最高。

If the disorder repair for the hepatic injury means possible carcinomatous change , does the oval cell take part in the formation of the hepatic cellular cancer ( HCC )?

肝损伤的异常修复就意味着可能癌变，作为肝干细胞代表的卵圆细胞是否也参与了原发性肝细胞癌（HCC）的形成？

They had round or oval cell nuclei , in which the nucleoli were evident , and vesicles and granules in cytoplasm .

倒置显微镜下观察，细胞呈扁平状，多边形，胞体较大，核圆形或椭圆形，核仁明显，胞质内含明显的颗粒和小泡。

Establish the rat model 2-AAF / PH ( forhepatic oval cell proliferation ), and the model of 2-AAF / PH + SPL .

建立肝卵圆细胞增殖模型（2-AAF/PH）和2-AAF/PH+SPL动物模型。

Conclusion The WNT signaling pathway plays a role in the process of hepatic oval cell activation , which is associated with the proliferation and differentiation of the hepatic oval cell .

WNT信号途径也参与了肝卵圆细胞活化的过程和肝卵圆细胞的增殖和分化相关。

Methods The model of hepatic oval cell proliferation was established by feeding 30 male Wistar rats with 0.06 % 3 ′ 3-diaminobenzidine ( DAB ) for 4 weeks .

方法30只雄性Wistar大鼠喂含0·06%的3-甲基-4-二甲基偶氮苯（DAB）的饲料4周，建立动物模型。

Results The overexpression of c Ha ras was closely associated with the formation and proliferation of the precancerous basophilic hepatocyte foci , while that of c myc with the growth of the oval cell foci .

结果cHaras和cMyc基因的过表达参与了肝癌变的全过程，其中cHaras的过表达与癌前嗜碱性肝细胞灶、cMyc基因的过表达与卵圆细胞增殖关系密切。

The markers such as A6 antigen , which is expressed by hepatic oval cell , are detected by means of immunocytochemistry . As the descendants of mouse ES cells , hepatic oval cells sorted by FACS were detected by RT-PCR and transmission electron microscopy .

其间用免疫细胞化学（ICC）检测肝卵圆细胞标志物A6等的表达，用流式细胞仪筛选肝卵圆细胞并行RT-PCR、透射电镜检测。

Results Cytokeratin 7-positive cells were observed in 68.1 % of primary hepatocellular carcinoma , characterized by oval cells-like stem cell or differentiated transitional-type cells .

结果68.1%肝细胞癌组织表达CK7，阳性细胞呈卵圆细胞样干细胞或过渡型分化细胞特征。

Application Yihong-hematoxylin staining ( HE ) can be observed in the purified cells , which have diverse polygonal , oval , clear cell boundaries . The cells have transparent cytoplasm , round nuclear or a small bubble .

应用伊红-苏木素染色法（HE），可观察到纯化的细胞形态多样，呈多角形或卵圆形，细胞界限清楚，胞浆透明，核圆或呈小泡状。

By electron microscope , shows the late vascular smooth muscle cells increased , increasing the oval cells , the cell rough endoplasmic reticulum 2 .

电镜下，晚期可见血管壁平滑肌细胞数量增多，细胞增大呈椭圆形，细胞内粗面内质网增多。

RESULTS : The expression of AFP and Ha-ras , c-myc genes in the cultured oval cells from different phases was synchronous : At the beginning of oval cell cultivation in vitro , both of AFP and oncogenes displayed a higher level expression and then declined .

结果：AFP及c-ras、c-myc在卵圆细胞体外培养的不同时期呈现同步升高或降低：培养初期，卵圆细胞AFP及癌基因均呈高表达，而后下降；

During the process of embryogenesis , hepatic stem cells presented as small hepatocytes and as oval cells in the liver tissue in adult mammal . The characters of oval cell are small and oval-shaped , big nucleus and rare plasm .

在胚胎发育过程中肝脏干细胞以肝细胞的形式存在，在成年哺乳动物的肝组织中以OVC存在，其特点是细胞小，呈卵圆型，核大而胞浆少。

Results : Hepatic oval cells proliferation was successfully induced in 2-AAF / PH model , and the proliferation peak presented in the tenth day after surgery , no hepatic oval cell in the control group .

结果2-AAF/PH模型成功诱导肝卵圆细胞增殖，同时还发现肝卵圆细胞的增殖高峰在术后10天左右，对照组无肝卵圆细胞出现。